The Bogotá-based artist Doris Salcedo, who has macular degeneration, has been making sculptures and public installations in response to political violence since the early 1990s. Until recently, her work primarily concerned the more than 90,000 Colombians who have disappeared in the past fifty years, 70,000 of them without a trace. That we might remember the disappeared, that we might know and remember the pain of those left behind, she made it her mission to materialize absence, to evoke the memories and images that are still present in the seemingly empty spaces where the living were murdered, or from which they vanished. Read on for an interview with Salcedo on her vision and art as a way of thinking, as well as reflections on her recent exhibition at the Harvard Art Museums.